Category publikáció

Absztrakt The development of copper(II) thiosemicarbazone complexes as potential anticancer agents, possessing dual functionality as inhibitors of R2 ribonucleotide reductase (RNR) and tubulin polymerization by binding at the colchicine site, presents a promising avenue for enhancing therapeutic effectiveness. Herein, we…

Absztrakt Multiple separate repair mechanisms safeguard the genome against various types of DNA damage, and their failure can increase the rate of spontaneous mutagenesis. The malfunction of distinct repair mechanisms leads to genomic instability through different mutagenic processes. For example, defective mismatch repair causes high base…

ZEEBONE, YARSMIN YUNUS ; BÓTA, BRIGITTA; HALAS, VERONIKA; LIBISCH, BALÁZS; OLASZ, FERENC; PAPP, PÉTER; KERESZTÉNY, TIBOR; GERŐCS, ANNAMÁRIA; ALI, OMERALFAROUG; KOVÁCS, MELINDA ET AL. Gut-Faecal Microbial and Health-Marker Response to Dietary Fumonisins in Weaned Pigs TOXINS 15 : 5 Paper: 328 , 18 p. (2023) Munkacsoport: Élelmiszerbiztonság

ZEEBONE, YARSMIN YUNUS ; BÓTA, BRIGITTA; HALAS, VERONIKA; LIBISCH, BALÁZS; OLASZ, FERENC; PAPP, PÉTER; KERESZTÉNY, TIBOR; GERŐCS, ANNAMÁRIA; ALI, OMERALFAROUG; KOVÁCS, MELINDA ET AL. Gut-Faecal Microbial and Health-Marker Response to Dietary Fumonisins in Weaned Pigs TOXINS 15 : 5 Paper: 328 , 18 p. (2023) Munkacsoport: Élelmiszerbiztonság

ZEEBONE, YARSMIN YUNUS ; BÓTA, BRIGITTA; HALAS, VERONIKA; LIBISCH, BALÁZS; OLASZ, FERENC; PAPP, PÉTER; KERESZTÉNY, TIBOR; GERŐCS, ANNAMÁRIA; ALI, OMERALFAROUG; KOVÁCS, MELINDA ET AL. Gut-Faecal Microbial and Health-Marker Response to Dietary Fumonisins in Weaned Pigs TOXINS 15 : 5 Paper: 328 , 18 p. (2023) Munkacsoport: Élelmiszerbiztonság

Absztrakt Identifying genes with prognostic significance that can act as biomarkers in solid tumors can help stratify patients and uncover novel therapy targets. Here, our goal was to expand our previous ranking analysis of survival-associated genes in various solid tumors to include colon…

Absztrakt The clinical success of PARP1/2 inhibitors (PARPi) prompts the expansion of their applicability beyond homologous recombination deficiency. Here, we demonstrate that the loss of the accessory subunits of DNA polymerase epsilon, POLE3 and POLE4, sensitizes cells to PARPi. We…

Absztrakt Complement is an ancient and complex network of the immune system and, as such, it plays vital physiological roles, but it is also involved in numerous pathological processes. The proper regulation of the complement system is important to allow…

Absztrakt A propylphosphonic anhydride (T3P®)-mediated new multicomponent method was developed for the synthesis of benzo[de]isoquinolinones bearing a phosphonate or a phosphine oxide moiety as a new family of compounds. The one-pot three-component reaction of 1,8-naphthalaldehydic acid, primary amines and dialkyl…

Absztrakt A series of new dialkyl α-diethylphosphonoylethyl-α-hydroxy-ethylphosphonates were prepared using the Pudovik reaction of the corresponding γ-oxophosphonate with dialkyl phosphites performed on the surface of Al2O3 The adducts revealed unexpected reactivity in the attempted O-acylation reaction, and provided the corresponding…